Treating the brain's circuits directly, with care led by a psychiatrist who researches them: how iTBS, deep TMS and tDCS work, the evidence by condition, safety and what to expect.
Interventional psychiatry and neuromodulation at Healthy Minds India, Patna, serving patients across India. Part of the published research write-ups.
Brain stimulation is suddenly in the news, from memory research to athletes training their minds. For many of my patients it is something more personal: it is the treatment that helped after medicines and therapy were not enough. I am Dr. Saurabh Kumar, a neuropsychiatrist trained at AIIMS New Delhi. For more than a decade I have delivered, studied and published on repetitive transcranial magnetic stimulation (rTMS). At Healthy Minds India in Patna, I have brought together theta burst stimulation (iTBS), deep TMS, tDCS, fNIRS brain imaging, EEG-based brain mapping and biofeedback under one roof. Patients travel to us from Bihar, Jharkhand, Uttar Pradesh, West Bengal, Nepal and across India. My aim is simple: to run a brain stimulation clinic in India that offers evidence-based brain stimulation therapy for depression, OCD and other conditions, explained honestly and delivered with precision.
01 · The basics
Every thought, mood and habit runs on electrical signals travelling through networks of brain cells. In depression, OCD or chronic pain, some of these networks become stuck: underactive in one place, overactive in another. Non-invasive brain stimulation gently nudges these circuits back towards healthy activity from outside the head. There is no surgery, no injection and no anaesthesia. You stay awake, and you can go back to work or college the same day.
It works through neuroplasticity, the brain's natural ability to rewire itself. Repeated sessions strengthen weak connections and calm overactive ones, much as regular exercise strengthens a muscle. My clinic uses two families of treatment and a third family of tools to measure the brain before and after treatment.
Most clinics stimulate and then ask how you feel. I prefer to measure. Rating scales tell us how you are doing. Brain and body measures add an objective second view of what is changing.
02 · Our technologies
Each tool has a specific job. Together they let me personalise treatment in a way no single device can.
| Tool | What it is | Evidence and source |
|---|---|---|
| iTBS: intermittent theta burst stimulation | Our signature protocol. iTBS delivers magnetic pulses in rapid bursts that mimic the brain's own natural theta rhythm, the rhythm it uses when it learns. A treatment session takes about 3 minutes instead of 37. | In the landmark THREE-D trial of 414 patients, published in The Lancet, it worked as well as conventional rTMS. The US FDA cleared it for depression in 2018.1 |
| Deep TMS: H7 coil | A specially shaped "H" coil reaches deeper and broader brain regions than a standard coil. The H7 targets the medial prefrontal and anterior cingulate cortex, the circuit at the heart of OCD. | FDA-cleared for OCD in 2018 after a multicentre trial published in the American Journal of Psychiatry.2 |
| tDCS in the clinic | A gentle, silent, direct current delivered under supervision, often at the same time as cognitive training or therapy. It is well suited to depression, to reducing cravings, and to people who prefer the lightest-touch option. | International guidelines rate it as probably effective (Level B) for depression.6 |
| App-guided tDCS, supervised continuation | After initial sessions in the clinic, suitable patients can continue with an app-connected device. I prescribe the protocol, lock the settings and monitor each session remotely. This is never do-it-yourself stimulation. | A trial in Nature Medicine showed that supervised home tDCS significantly improved depression compared with sham.4 |
| fNIRS: functional near-infrared spectroscopy | A lightweight headband shines safe near-infrared light to measure oxygen use in the frontal lobe while you do simple tasks. I use it to see how the frontal brain responds before and after treatment. | In Japan, fNIRS has been used as an aid in the assessment of depressive states for over a decade.19 |
| EEG and qEEG brain mapping | A standard clinical EEG records the brain's electrical rhythms. Quantitative (qEEG) analysis turns these recordings into colour maps and comparisons. It helps screen for abnormalities before stimulation and documents change over a course. | A supportive tool, interpreted alongside clinical assessment. |
| Biofeedback: heart rate variability, breathing, skin conductance | Sensors show your heart rhythm, breathing and stress responses on a screen in real time, so you can learn to control them. It pairs naturally with stimulation for anxiety, panic, insomnia and headache. | A meta-analysis of 24 studies found a large reduction in stress and anxiety with HRV biofeedback (effect size 0.81).16 Biofeedback also reduces migraine frequency.17 |
03 · Why theta burst
Both are proven. iTBS gives the same benefit in a fraction of the time, which makes daily treatment far easier to fit around work, college and travel.
| Feature | Conventional 10 Hz rTMS | iTBS (theta burst) |
|---|---|---|
| Stimulation time per session | About 37.5 minutes | About 3 minutes |
| Pulses per session | 3,000 | 600, delivered in natural theta-rhythm bursts |
| Effectiveness in depression | Proven in many sham-controlled trials | Non-inferior to rTMS in THREE-D (n = 414); response about 49%, remission about 32% in a treatment-resistant group |
| US FDA clearance for depression | 2008 | 2018 |
| Accelerated (multiple sessions a day) options | Impractical because of session length | Feasible. An accelerated iTBS protocol (SAINT) was FDA-cleared in 2022 after 78.6% remission versus 13.3% with sham in its controlled trial3 |
| Side effects | Mild scalp discomfort and headache | Similar; some people find the bursts a little more noticeable in the first few sessions |
| Time off work or study | Around an hour a day including set-up | Often under 20 minutes door to door once settled |
| Feature | Standard figure-8 coil | Deep TMS H7 coil |
|---|---|---|
| Reach | Focused, superficial cortex | Deeper and broader: medial prefrontal and anterior cingulate cortex |
| Best-established use | Depression (left prefrontal) | Treatment-resistant OCD, FDA-cleared in 2018 |
| OCD trial result | Various targets; results vary between studies | Response 38.1% vs 11.1% sham after 6 weeks; 45.2% vs 17.8% at one-month follow-up |
| Session design | About 3 to 37 minutes depending on protocol | About 20 minutes, preceded by a brief, guided symptom provocation |
| Seizure risk | Extremely rare | Still rare, but somewhat higher per patient, so screening is stricter |
| Tool | What it does | Session | Main strengths | Where I use it most |
|---|---|---|---|---|
| iTBS | Magnetic bursts that strengthen a target circuit | About 3 min | Level A evidence, FDA-cleared, fast | Depression, anxious depression, some OCD and pain protocols |
| Deep TMS H7 | Deeper magnetic stimulation | About 20 min | FDA-cleared for OCD | Treatment-resistant OCD |
| tDCS (clinic) | Weak current that primes circuits | 20 to 30 min | Very gentle, pairs with training | Depression, craving, cognitive training |
| tDCS (app-guided) | Supervised continuation | 20 to 30 min | Fewer visits, RCT-backed | Maintenance, outstation patients |
| Biofeedback | Trains control of stress physiology | 30 to 45 min | Strong HRV evidence, skill for life | Anxiety, panic, headache, sleep, performance |
| fNIRS | Measures frontal-lobe blood flow | 20 to 30 min | Objective before and after data | Baseline and follow-up measurement |
| EEG / qEEG | Records and maps brain rhythms | 30 to 45 min | Safety screening, brain mapping | Pre-treatment screening, cognitive and attention complaints |
04 · TMS versus tDCS
TMS makes brain cells fire. tDCS makes them more ready to fire. TMS is the stronger, better-studied treatment for moderate to severe or treatment-resistant illness. tDCS is gentler, cheaper to run and portable, and it is best at boosting what therapy and training are already doing.
Often the answer is both, in sequence. A common plan is iTBS to bring about recovery, then supervised tDCS and biofeedback to keep it, with therapy running alongside throughout. The final decision comes after a full assessment: diagnosis, severity, past treatments, medical history, and your own preferences and practicalities.
05 · Conditions we treat
I grade every indication openly, using the European expert guidelines (Lefaucheur et al.), FDA clearances and major trials. You should know how strong the science is before you begin.5, 6
| Condition | Main approach | Evidence | Notes |
|---|---|---|---|
| Depression, including treatment-resistant depression | iTBS or rTMS, left prefrontal | Strong | Level A; FDA-cleared. The best-studied use of brain stimulation therapy for depression in India and worldwide. |
| Depression (mild to moderate, or maintenance) | tDCS, clinic or app-guided | Good | Level B; home tDCS RCT: 58.3% vs 37.8% response, 44.9% vs 21.8% remission.4 |
| Obsessive-compulsive disorder | Deep TMS H7; low-frequency rTMS (OFC/SMA) | Strong | H7 FDA-cleared in 2018. My own AIIMS research on orbitofrontal rTMS in drug-resistant OCD is summarised below. |
| Panic disorder and anxiety with depression | Prefrontal rTMS or iTBS plus biofeedback | Good | HRV biofeedback has strong anxiety evidence. My study found panic and depression both improved with rTMS. |
| PTSD | Right prefrontal rTMS | Good | Level B in the 2020 guidelines, used alongside trauma-focused therapy. |
| Craving in alcohol, opioid or nicotine use | tDCS (prefrontal), rTMS | Good | tDCS is Level B for craving; always combined with de-addiction care. |
| Negative symptoms and voices in schizophrenia | Prefrontal rTMS; temporoparietal low-frequency rTMS | Emerging | An add-on to medication, used selectively. |
| Migraine with depression | Prefrontal rTMS; biofeedback | Good | Biofeedback is well supported for migraine. My study showed reduced migraine disability with rTMS. |
| Tics and Tourette syndrome | Low-frequency rTMS over the SMA | Emerging | An area of my published research; considered case by case. |
| Tinnitus | Cathodal tDCS, temporoparietal | Emerging | My co-authored case series found improvement, with better results when started early. |
| Memory and attention difficulties | tDCS or tACS with cognitive training | Emerging | See the learning section below; always paired with structured training. |
Brain stimulation began in neurology, and some of its strongest evidence is there. I work with your neurologist or physiotherapist when these apply. The cards are grouped by how strong the evidence is.
Strong Level A evidence
High-frequency rTMS over the motor cortex on the opposite side to the pain, for example after nerve injury or in some post-stroke pain.
rTMS for motor symptoms and for the depression that often accompanies Parkinson's.
Low-frequency rTMS to the healthy hemisphere in the post-acute phase, combined with physiotherapy, to help the damaged side recover.
Good Level B evidence
rTMS, and tDCS paired with speech therapy. A randomised trial showed better naming with active tDCS than with sham.13
rTMS and tDCS over the motor cortex reduce widespread pain and improve quality of life.
iTBS over the motor cortex to reduce leg stiffness, alongside rehabilitation.
Also worth knowing: single-pulse TMS devices are FDA-cleared for migraine. See also neuropsychiatry at Healthy Minds India.
06 · In the news
The research here is genuinely exciting. Carefully timed stimulation, paired with practice, can strengthen the brain's learning machinery. These are the landmark findings.
What this means at Healthy Minds: the lesson from every study is the same: stimulation amplifies training; it does not replace it. In our cognitive lab, tDCS is paired with a structured, Hinglish-friendly programme of memory, attention and planning exercises. I use this for people whose thinking has been dulled by depression, for students and professionals with genuine attention or memory difficulties, and for older adults with early memory complaints. Results vary between individuals, so progress is measured with standard tests and, where useful, fNIRS or qEEG. For conditions such as depression and OCD, TMS remains my proven, first-line stimulation treatment.
Elite sport was among the first fields to take brain and body training seriously, because the smallest gain in calm, focus or reaction time decides medals.
India's first individual Olympic gold medallist trained with a sports psychophysiologist using biofeedback and neurofeedback: heart rate variability, breathing, thermal and skin-conductance feedback, and EEG training both in the chair and while shooting. The goal was to stay perfectly still and calm while remaining alert at the moment of the shot.18
150+ hours of training logged
The Italian football club built a dedicated biofeedback and neurofeedback centre to train players' stress control and recovery. The respiration techniques developed there were among those used in Bindra's preparation.
National players have trained with NeuroTracker, a 3D visual attention and processing-speed programme, to sharpen on-field awareness.
What controlled studies show
In a controlled study, 12 sessions of EEG neurofeedback improved reaction time in trained athletes. Reviews of neurofeedback in sport report better stress control and attention, although the trials are still small.
At Healthy Minds India: our biofeedback and cognitive-training programmes use the same principles for students preparing for NEET, JEE and civil services, for performers, and for anyone whose anxiety undermines performance under pressure. See biofeedback.
07 · Your first visit and beyond
How long a course lasts
Your plan is personalised to your diagnosis and response. Most people continue their usual medicines during treatment; I review every prescription beforehand, because a few medicines affect stimulation thresholds.
Depression is often a recurring illness. Recovering is one goal, and staying recovered is the next. Evidence now supports planned maintenance sessions after a successful course.
Response at 6 months after a course (pooled data from 18 studies, 732 patients)
A 2024 meta-analysis of 14 studies (705 patients) found that maintenance rTMS helps maintain remission and prevent relapse. "Rescue" sessions, added at the first signs of slipping, showed a stronger effect.14 A 2023 meta-analysis found maintenance kept mood stable for about five months, and monthly or more frequent sessions extended the benefit to 6 to 12 months.15 Supervised home tDCS gains were also maintained at 6 months.4 My approach: after a successful course, we taper gradually rather than stopping abruptly. Sessions move from daily to weekly and then monthly. We watch for early warning signs and give booster sessions promptly when they appear. For outstation patients, supervised app-guided tDCS can carry part of the maintenance.
08 · Is it safe?
Non-invasive brain stimulation is one of the best-tolerated treatments in psychiatry. There is no anaesthesia, no memory loss and no effect on weight or sexual function. Side effects are mild and short-lived.
| Side effect | How common | How long it lasts | Seriousness |
|---|---|---|---|
| Scalp discomfort or tapping sensation (TMS) | Common in early sessions | Only during the session; usually eases within the first week as you get used to it | Mild; the dose can be adjusted |
| Headache (TMS) | Common early on | Usually a few hours; responds to a simple painkiller and becomes less frequent after the first 1 to 2 weeks | Mild |
| Tingling, itching or warmth (tDCS) | Very common | During the first minute or so; fades as the session continues | Mild |
| Skin redness under the pads (tDCS) | Common | Fades within an hour; we check the skin every session | Mild; burns are prevented by correct set-up |
| Tiredness or light-headedness | Occasional | Minutes to hours | Mild |
| Seizure (TMS) | Very rare (see below) | Brief; stops on its own | Serious but short-lived, with no lasting harm in reported cases |
For tDCS, a large safety review covering more than 33,200 sessions in over 1,000 people found no serious adverse effects with standard protocols.10
Putting it in context: accelerated iTBS trials, which deliver 50 sessions in 5 days, reported no seizures. For comparison, a widely used antidepressant, bupropion, carries a seizure risk of about 1 in 1,000 patients at standard doses. That is well above the risk per TMS course. tDCS has not been shown to cause seizures. Our screening checks sleep, alcohol, medicines and personal and family seizure history before every course. A trained team is present during every session.7, 8, 9
Every protocol at Healthy Minds India follows published clinical guidelines. The type of stimulation, the number of sessions and the overall plan depend on your diagnosis, severity and early response, so I discuss them only after I have assessed you properly, never as a one-size-fits-all package. After your assessment, you will receive a clear, written explanation of the recommended treatment, its expected course, how we will measure progress and all related details. We believe in complete transparency, and there are no surprises midway.
09 · Research made simple
I do not just deliver brain stimulation. I have studied it, published on it and taught it. Here are my neuromodulation studies at a glance. The full list of about 59 publications is on the research page, and a plain-language summary of the OCD work is in rTMS for OCD: what a study of 79 patients found.
I have also published on rTMS in tic disorders and Tourette syndrome, on tDCS for opioid craving (Brain Stimulation 2019), on where rTMS stands in OCD (Neuropsychiatry 2016), and reported a first-of-its-kind case of new-onset OCD during rTMS for schizophrenia. That case is a reminder of why careful monitoring matters.
10 · About me
My interest in brain stimulation began at AIIMS New Delhi, where I trained in psychiatry. I later worked as Senior Resident and Senior Research Officer and studied patients treated in the institute's brain stimulation service. The questions I saw there shaped my research. Why does one person with OCD respond while another does not? Can one treatment ease both panic and depression? These questions led to peer-reviewed papers, international conference presentations and an abstract in Brain Stimulation. I also spent two years as Senior Registrar at the National Drug Dependence Treatment Centre (NDDTC), AIIMS, a WHO Collaborating Centre. That is where my work on craving and addiction comes from. I have taught psychiatry at Dr. RML Hospital in Delhi and at PMCH in Patna, and I now head the Department of Psychiatry at RDJM Medical College. I built the neuromodulation lab at Healthy Minds India so that patients in Bihar and eastern India would not need to travel to a metro city for care of this standard. Every patient is assessed by me personally. Every protocol is chosen from the evidence. Every result is measured. More on my profile page.
Frequently asked questions about brain stimulation treatment
TMS uses magnetic pulses that make brain cells fire. It is stronger and better proven for moderate to severe depression and OCD. tDCS uses a very weak current that makes cells more ready to fire. It is gentler, and it works best when combined with therapy or training. See TMS treatment.
No. You are awake throughout, with no anaesthesia and no fit induced. TMS feels like tapping on the scalp, and tDCS like a mild tingle. Neither affects memory.
Yes. In the largest head-to-head trial, 3-minute iTBS was as effective as the 37.5-minute standard protocol for depression, with similar side effects.
Published depression courses usually involve 20 to 30 sessions over 4 to 6 weeks. OCD and tDCS courses differ. You will get a clear, personalised plan after your assessment.
Controlled studies show that stimulation paired with practice can improve learning and memory, with benefits lasting weeks to months. It amplifies training rather than replacing it, and results vary. It is offered within a structured, measured cognitive programme.
They show how your frontal brain and brain rhythms are working, and how these change with treatment. They support clinical judgement but do not replace a psychiatric diagnosis.
People with metal implants in the head, cochlear implants or implanted electronic devices near the coil. People with epilepsy, recent head injury or pregnancy need individual assessment first.
The plan depends on your diagnosis, the protocol and your response, so full details are shared transparently after your assessment, before you begin.
In most cases, yes. Stimulation is usually added to your current treatment. Your prescriptions are reviewed first, because a few medicines need adjustment.
Yes. Many of our patients come from other districts and states. The initial course is planned efficiently, and suitable patients can continue maintenance through supervised, app-guided tDCS with online reviews.
Yes. Healthy Minds India in Patna offers iTBS, rTMS, deep TMS (H7 coil), tDCS, fNIRS, EEG/qEEG and biofeedback under one roof, led by an AIIMS-trained neuropsychiatrist. Patients come from Bihar, Jharkhand, Uttar Pradesh, West Bengal and Nepal.
For many people, yes. Planned maintenance sessions significantly reduce relapse, and you are monitored so that booster sessions can start early if needed.
Key references, in order of first mention.
© 2026 Healthy Minds India, Patna · Edition 1.0, September 2026, 2026
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For general education; not a substitute for a personal consultation. If you or someone close to you is in distress, please speak to a qualified mental health professional.
Medically reviewed by Dr. Saurabh Kumar, Consultant Neuropsychiatrist, Healthy Minds India, Patna. This article is for general education and is not a substitute for a personal consultation. To discuss your situation, book an appointment or contact the clinic.
Disclaimer: all characters and events depicted in this blog are entirely fictional. Any resemblance to actual persons, living or dead, is purely coincidental. The content is intended for informational purposes only and should not be considered medical advice. Always consult a qualified healthcare professional for medical concerns.
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